The Acute Kidney Injury (AKI) Clinical Domain Team aims to investigate risk factors associated with kidney injury and recovery, as well as use of angiotensin-converting enzyme (ACE) inhibitors and angiotensin II receptor blockers (ARBs) in kidney disease. Their research involves the assessment of risk factors, predictors, duration, dialysis need and timing, clinical measures, and interventions for COVID-19-related complications of the kidney. The team also collaborates with other nephrology domain experts.
Team meets every Wednesday at 4:00 PM ET. Please email n3c-tt-akiarbace@googlegroups.com to be added to the calendar invite.
","The Acute Kidney Injury (AKI) Clinical Domain Team aims to investigate risk factors associated with kidney injury and recovery, as well as use of angiotensin-converting enzyme (ACE) inhibitors and angiotensin II receptor blockers (ARBs) in relation to COVID-19.
","n3c-tt-akiarbace@googlegroups.com","https://groups.google.com/forum/#!managemembers/n3c-tt-akiarbace","Join the Team!","https://drive.google.com/drive/u/0/folders/1LVsdcP0nOy9132AoSGVOJ-pSfn2OxQ1o","AKI Drive","https://cd2h.slack.com/archives/C01BN11EMPH","Join the Conversation","2020-10-01 01:01:37-05","2021-05-05 13:33:59-05" 369,4936,"Applicable Data Methods & Standards (ADM&S)",1,"The Applicable Data Methods & Standards (ADM&S or "AD-MetS") Domain Team aims to explore which data methods & standards are applicable to the range of questions researchers will pursue within N3C, with some near-term and longer-term activities outlined below. A mission statement is currently being formed around thematic goals:
Team meetings are held every Wednesday at 8:00am PT/11:00am ET. To join this call, please register here.
","
The Applicable Data Methods & Standards (ADM&S) Domain Team aims to explore which data methods & standards are applicable to the range of questions researchers will pursue within N3C.
","n3c-tt-applicable-data-methods-standards@googlegroups.com","https://groups.google.com/forum/#!forum/n3c-tt-applicable-data-methods-standards","Join the Team!","https://drive.google.com/drive/u/0/folders/1LVsdcP0nOy9132AoSGVOJ-pSfn2OxQ1o","ADM&S Drive","https://cd2h.slack.com/archives/C015R3JN3U5","Join the Conversation","2020-10-02 15:05:58-05","2021-10-27 09:53:45-05" 487,4363,"COVID-19 Vaccination",0,"The goal of this Domain Team is to study the impact of vaccinations in combating the COVID-19 pandemic. As multiple vaccines become available, we will focus on how these vaccines perform in the real world setting of heterogeneous populations and serovariants.
Team meeting TBD.
","The goal of this Domain Team is to study the impact of vaccinations for combating the COVID-19 pandemic.
","n3c-dt-covid-vaccination@googlegroups.com","https://groups.google.com/u/2/g/n3c-dt-covid-vaccination","Join the Team!","https://drive.google.com/drive/u/2/folders/1GayDddKp83DZ3aCDEUYCGtrHT7ih5ql7","Vaccination Drive","https://join.slack.com/share/zt-mc2mv97o-iedK6zAZvsQTmG1wxo7m4A","Join the Conversation","2021-02-12 11:42:58-06","2021-05-05 14:11:49-05" 557,4509,"Cardiothoracic and Vascular Surgery",0,"The Cardiothoracic and Vascular Surgery Domain Team seeks to establish risk factors for morbidity and mortality in COVID-19 patients who underwent cardiothoracic surgical procedures.
Initial meeting: April 15, 2021 at 12:00pm ET. Recurring meeting TBD.
","The Cardiothoracic and Vascular Surgery Domain Team seeks to establish risk factors for morbidity and mortality in COVID-19 patients who underwent cardiothoracic surgical procedures.
","n3c-dt-cardiothoracic-and-vascular-surgery@googlegroups.com","https://groups.google.com/u/1/g/n3c-dt-cardiothoracic-and-vascular-surgery","Join the Team!","https://drive.google.com/drive/u/0/folders/1u_l_coIcTJbPqqXGp_PYebGsiEFLAtPN","Cardiothoracic and Vascular Surgery","https://cd2h.slack.com/archives/C021E4GK7RC","Join the Conversation","2021-05-12 16:06:59-05","2021-05-24 12:45:52-05" 438,5254,"Cardiovascular Disease",0,"Meeting Time: Meetings are held bi-weekly at 5:00pm eastern standard time on Tuesdays starting October 19, 2021. Please email n3c-dt-cardiology@googlegroups.com to be added to the calendar invite.
The mission of the Cardiovascular Disease Clinical Domain Team is to better understand the effects of COVID-19 on patients with new and existing cardiovascular disease including, but not limited to, acute myocardial infarction, congestive heart failure, stroke, and coronary artery disease to determine the effect of COVID-19 on outcomes including mortality, hospitalization, and access to care.
The mission of the Cardiovascular Disease Clinical Domain Team is to better understand the effects of COVID-19 on patients with new and existing cardiovascular disease.
","n3c-dt-cardiology@googlegroups.com","https://groups.google.com/forum/#!forum/n3c-dt-cardiology","Join the Team!","https://drive.google.com/drive/u/0/folders/1zXM-PiiEnTmEz8vOSth8PVOAHZcVSw1c","Cardiology Drive","https://cd2h.slack.com/archives/C01MN9Y9DK8","Join the Conversation","2020-11-25 16:51:30-06","2022-04-28 10:24:33-05" 364,4405,"Critical Care, Ventilation, Multi-organ Dysfunction Syndrome (MODS)",0,"The Critical Care/Ventilation/Multi-organ Dysfunction Syndrome (MODS) Clinical Domain Team, one of few ?joint? N3C Domain Teams, aims to better understand and characterize complex disease trajectories including multiple organ dysfunction, along with determination of treatment efficacies to improve outcomes in critically ill patients with COVID-19. The vision of the Critical Care/Ventilation/MODS Domain Team is to understand the pathophysiology of the SARS-CoV-2 virus on single and multi-organ systems, and what determines optimal treatment strategies affecting short- and longer-term outcomes of critically ill COVID-19 patients. The ventilation subgroup is focused on defining critical care cohorts based on ventilation strategies, as well as studying clinical outcomes on intubated patients versus those not intubated. The MODS subgroup focuses on characterizing multi-organ dysfunction as a temporal trajectory and probabilistic process.
Both subgroups are actively soliciting members to join and contribute to the goals and mission of this highly unique domain team.
Team meeting every other Thursday from 1:00 - 1:45 pm ET. Please email n3c-tt-decompensation-multi-organ-dysfunction@googlegroups.com to be added to the calendar invite.
","The Critical Care/Ventilation/Multi-organ Dysfunction Syndrome (MODS) Clinical Domain Team aims to define and characterize the phenotypes of multiple organ dysfunction and complex disease trajectories among hospitalized patients with COVID-19.
","n3c-tt-decompensation-multi-organ-dysfunction@googlegroups.com","https://groups.google.com/d/forum/n3c-tt-criticalcare","Join the Team!","https://drive.google.com/drive/u/0/folders/1LVsdcP0nOy9132AoSGVOJ-pSfn2OxQ1o","MODS Drive","https://cd2h.slack.com/archives/C01BN143UGP","Join the Conversation","2020-10-02 14:53:29-05","2021-05-06 14:43:06-05" 340,4968,"Diabetes & Obesity",0,"The Diabetes and Obesity Clinical Domain Team aims to address questions regarding who among people with diabetes and/or obesity are likely to experience poor outcomes in the setting of COVID-19. Though hundreds of papers have been written on this topic, most involve small sample size, single centers, international data resources or other characteristics that leave unanswered questions. Three protocols have been drafted to examine: (1) Effect of glycemic control on COVID-19 outcomes, (2) COVID-19 outcomes as a function of metformin use, and (3) Comparative effectiveness research on COVID-19 outcomes as a function of antihyperglycemic medication use at baseline. The overall goal is to evaluate baseline factors for effects on COVID-19 outcomes in diabetes.
Team meeting on the 4th Thursday of the month at 9:00am ET. Please email n3c-tt-diabetes@googlegroups.com to be added to the calendar invite.
","The Diabetes and Obesity Clinical Domain Team aims to address questions regarding who among people with diabetes and/or obesity are likely to experience poor outcomes in the setting of COVID-19.
","n3c-tt-diabetes@googlegroups.com","https://groups.google.com/forum/#!forum/n3c-tt-diabetes","Join the Team!","https://drive.google.com/drive/u/0/folders/1LVsdcP0nOy9132AoSGVOJ-pSfn2OxQ1o","Diabetes & Obesity Drive","https://cd2h.slack.com/archives/C01BEL0G5S6","Join the Conversation","2020-10-01 01:01:38-05","2021-12-16 10:12:25-06" 595,5069,"Education and Training",1,"The ET-DT will house education-related DURs and provide support to mentors, instructors, and learners (we will also encourage teams to affiliate with clinical DTs where appropriate). This domain team will also be used to discuss and coordinate N3C-specific education and training efforts (such as the Enclave Users? Group and N3C training modules), develop N3C-related funding opportunities (e.g., NIH R25 grant submissions), and related efforts (e.g., development of a short course and open-access educational materials such as an online book).
Meeting information: Meetings are held bi-weekly on Thursdays at 9am PT / 12:00pm ET starting 01/20/2022
","The Education and Training Domain Team will house education-related data use requests and provide support to mentors, instructors, and learners.
","n3c-edu@ctsa.io","null","null","https://drive.google.com/drive/u/0/folders/1_t-7454NPxaEbsposubQl7LXdp7Z2BO5","Education and Training Domain Team Google Drive","https://cd2h.slack.com/archives/C02T6M3T3SS","Join the conversation","2022-01-06 09:45:42-06","2022-02-11 10:33:41-06" 365,4367,"Elder Impact",0,"The Elder Impact Clinical Domain Team aims to complete a descriptive study to illustrate the impacts of COVID-19 on older adults and those with dementia/functional limitations. This includes (1) the use and safety of available COVID therapies in older patients, (2) the severity of COVID-19 among older adults with and without chronic diseases, and (3) the mental health impact of the COVID-19 pandemic on older adults.
Team meeting every other Thursday at 12:00pm ET. Please email n3c-tt-elder-impact@googlegroups.com to be added to the calendar invite.
","The Elder Impact Clinical Domain Team aims to complete a descriptive study to illustrate the impacts of COVID-19 on older adults and those with dementia/functional limitations.
","n3c-tt-elder-impact@googlegroups.com","https://groups.google.com/forum/#!forum/n3c-tt-elder-impact","Join the Team!","https://drive.google.com/drive/u/0/folders/1LVsdcP0nOy9132AoSGVOJ-pSfn2OxQ1o","Elder Impact Drive","https://cd2h.slack.com/archives/C018QRL66MV","Join the Conversation","2020-10-02 14:56:43-05","2021-05-05 14:20:39-05" 510,4369,"Environmental Health",0,"The Environmental Health Domain Team aims to study and understand the impact of environmental exposures on post-acute sequelae of COVID (PASC), also known as Long COVID, and other COVID-19 phenotypes. This team will take a "total environment" view and examine multiple environmental media and time frames of exposure. Through collaborations with other Domain Teams (e.g. SDoH), we will also examine social exposures and the intersection of social and chemical environmental exposures, e.g. environmental justice.
Team meeting every other Thursday at 3:00pm ET. Please email n3c-dt-env-health@googlegroups.com to be added to the invite.
","The Environmental Health Domain Team aims to study and understand the impact of environmental exposures on post-acute sequelae of COVID (PASC), also known as Long COVID, and other COVID-19 phenotypes.
","n3c-dt-env-health@googlegroups.com","https://groups.google.com/u/2/g/n3c-dt-env-health","Join the Team!","https://drive.google.com/drive/folders/1C-Abkmk7OZWRVrE344e5e8yTaGNp7710?usp=sharing","Environmental Health Drive","https://cd2h.slack.com/archives/C01SV2LUY75","Join the Conversation","2021-03-25 12:49:41-05","2021-05-05 14:23:42-05" 626,5144,"GIS and Spatial Epidemiology",0,"The mission of the GIS and Spatial Epidemiology (GSE) Domain will be to facilitate the technical implementation of basic and advanced GIS and spatial statistical methods within the National COVID Cohort Collaborative database. Our group will also provide expertise to other domains interested in applying spatial statistical or epidemiological methods within the scope of their work.
Meeting information: Meetings are held bi-weekly on Thursdays at 4:00pm EST starting February 10th.
","The GIS and Spatial Epidemiology (GSE) domain team facilitates the technical implementation of basic and advanced GIS and spatial statistical methods within the N3C Enclave.
","n3c-gis-dt@ctsa.io","https://groups.google.com/a/ctsa.io/g/n3c-gis-dt","Join the team!","https://drive.google.com/drive/u/0/folders/1T0WkhXCgaxiZOHnnnUPJ5wO1nvdX-TWE","GIS and Spatial Epidemiology Domain Team Google Drive","https://cd2h.slack.com/archives/C036AJSF1EZ","Join the conversation","2022-03-14 11:06:25-05","2022-03-15 11:31:50-05" 534,4347,"Gastroenterology and Hepatology (GI/Liver)",0,"The Gastroenterology and Hepatology Domain Team aims to gain a better understanding of how SARS-Cov-2 infection affects patient populations with chronic gastrointestinal and liver diseases?including, but not limited to, inflammatory bowel diseases, diseases of the biliary tract, chronic hepatitis, cirrhosis, and gastrointestinal cancers. The initial research of this Domain Team will focus on the outcomes of SARS-CoV-2 infection in patients with cirrhosis and patients with chronic liver diseases.
Team meetings are held on the 3rd Monday of the month (beginning May 17th) at 10:00am PT/1:00pm ET. Please email n3c-dt-liver@googlegroups.com for meeting link.
","The Gastroenterology and Hepatology Domain Team aims to gain a better understanding of how SARS-Cov-2 infection affects patient populations with chronic gastrointestinal and liver diseases.
","n3c-dt-liver@googlegroups.com ","https://groups.google.com/g/n3c-dt-liver","Join the Team!","https://drive.google.com/drive/u/0/folders/12dwrPKAeFUwfiw0jNYcuOsesGamx80Cd","GI/Liver Drive","https://cd2h.slack.com/archives/C01TYTJ35U5","Join the Conversation","2021-04-08 17:58:40-05","2021-05-05 13:47:16-05" 439,4404,"Genomics",1,"The Genomics Domain Team will explore issues related to genomics and COVID-19. More details on specific goals and leadership coming soon.
Pending.
","The Genomics Domain Team will explore issues related to genomics and COVID-19.
","n3c-dt-genomics@googlegroups.com","https://groups.google.com/forum/#!forum/n3c-dt-genomics","Join the Team!","https://drive.google.com/drive/u/0/folders/13qL80ev3fHTaW7VNIVlf7BKE8QZV5RIZ","Genomics Drive","null","null","2020-11-25 16:58:31-06","2021-05-06 14:39:20-05" 524,4370,"Hematology",0,"The goal of the Hematology Domain Team is to use the N3C Data Enclave to characterize the epidemiology, outcomes, and severity of COVID-19 in patients with a broad spectrum of hematological diseases. This team will primarily focus on benign hematological diseases and will include the following conditions:
Hemoglobin disorders: hemoglobinopathy, thalassemia
Bleeding disorders: Hemophilia & Hemophilia B, von Willebrand?s disease, platelet function disorders and other rare bleeding disorders
Thromobophilic conditions: Factor V Leiden, prothrombin gene mutation, deficiencies of proteins C, S, antithrombin, antiphospholipid antibody, and similar conditions
Post-splenectomy
Thrombocytopenia
Team meeting TBD.
","
The goal of the Hematology Domain Team is to use the N3C Data Enclave to characterize the epidemiology, outcomes, and severity of COVID-19 in patients with a broad spectrum of hematological diseases.
","n3c-dt-hematology@googlegroups.com","https://groups.google.com/u/2/g/n3c-dt-hematology","Join the Team!","https://drive.google.com/drive/folders/162xbldoOlxWZYr71w7sQowzLjN87outT?usp=sharing","Hematology Drive","https://cd2h.slack.com/archives/C01T0D93CQ3","Join the Conversation","2021-03-29 12:10:45-05","2021-05-05 14:25:47-05" 378,4403,"Imaging",0,"The clinical research objectives of this group are to explore (1) knowledge that can be gained about the relationship between radiological imaging features and COVID-19 clinical course, clinical manifestations, comorbidities, (2) the ability of radiological images combined with other clinical and demographic variables to predict disease course, severity, sequelae, and long-term disease impact, and (3) the ability of combined radiology imaging information and clinical and demographic variables to predict disease course, organ system involvement, severity, and development of chronic post-COVID-19 syndromes. The infrastructure development objectives of this group are to develop software infrastructure to link outside sources of images and imaging features to the N3C Data Enclave, as well as to be an early adopter of the hashing method for linking TCIA imaging data to N3C data.
Pending.
","The Imaging Domain Team seeks to explore the knowledge that can be gained about the relationship between radiological imaging features and COVID-19 as well as to identify and better understand what variables in this space can be used to predict disease and outcome characteristics.
","n3c-tt-imaging@googlegroups.com","https://groups.google.com/forum/#!forum/n3c-tt-imaging","Join the Team!","https://drive.google.com/drive/u/0/folders/1LVsdcP0nOy9132AoSGVOJ-pSfn2OxQ1o","Imaging Drive","https://cd2h.slack.com/archives/C01BZLEATS9","Join the Conversation","2020-10-06 15:59:56-05","2021-05-06 14:37:48-05" 341,5061,"Immunosuppressed or Compromised (ISC)",0,"The Immunosuppressed/Compromised (ISC) Clinical Domain Team aims to gain a better understanding of how COVID-19 affects patient populations with suppressed or compromised immune systems. The initial research will focus on a subset of target populations, including persons with HIV, solid organ transplant patients, and patients with autoimmune disorders, including skin diseases such as atopic dermatitis and eczema. The team will also identify areas of research for the ISC populations that will require additional in-depth study at a level that the N3C data may not be able to provide. Through this research, a better understanding will be gained for how various types, levels, and durations of immunosuppression or compromise contribute towards ISC patient outcomes upon COVID-19 infection.
Team meetings are held on the 1st Friday of the month at 8:00am PT/11:00am ET. Register for meetings here.
","The Immunosuppressed/Compromised (ISC) Clinical Domain Team aims to gain a better understanding of how COVID-19 affects patient populations with suppressed or compromised immune systems.
","n3c-tt-immuno-suppressed-compromised@googlegroups.com","https://groups.google.com/forum/#!forum/n3c-tt-immuno-suppressed-compromised/","Join the Team!","https://drive.google.com/drive/u/0/folders/1tUx2aSOexAPvlchIwkR_YT_D0tlIfCgF","ISC Drive","https://cd2h.slack.com/archives/C01A0GBSV0C","Join the Conversation","2020-10-01 01:01:39-05","2022-02-03 15:32:32-06" 550,5032,"Lifespan Disabilities",0,"The mission of the Lifespan Disabilities Domain Team is to advance practices and policies that improve the education, access, and health of all people with developmental and other disabilities, as well as their families, by examining extent to which individuals with disabilities have been affected by COVID-19 diagnoses and access to appropriate treatments and follow up.
Meeting time: The third Friday of each month at 10:00am PT / 1:00pm ET.
","The mission of the Lifespan Disabilities Domain Team is to advance practices and policies that improve the education, access, and health of all people with developmental and other disabilities.
","n3c-dt-lifespan-disabilities@googlegroups.com","https://groups.google.com/g/n3c-dt-lifespan-disabilities","Join the Team!","https://drive.google.com/drive/u/0/folders/14rmIs4LYDco9M7YuHk7tfho2-SYP1PTy","Lifespan Disabilities","https://cd2h.slack.com/archives/C0207AC9DA6","Join the Conversation","2021-04-27 15:31:46-05","2022-01-18 10:35:13-06" 479,4373,"Long COVID",0,"This project aims to define and characterize patients with long-term sequelae of SARS-CoV-2 infection. A Long-COVID phenotype will support prognostic characterization of different substrata, potentially more precise care management, and greatly inform prospective interventional studies.
Team meeting are held every Thursday at 7:00am PT/10:00am ET. Register for meetings here.
","This project aims to define and characterize patients with long-term sequelae of SARS-CoV-2 infection.
","n3c-dt-longcovid@googlegroups.com","https://groups.google.com/g/n3c-dt-longcovid","Join the Team!","https://drive.google.com/drive/u/0/folders/1oumtq6iZLjNDZS_g5bh6DGIJtthP31SK","Long COVID Drive","https://cd2h.slack.com/archives/C01N8BA8S73","Join the Conversation","2021-02-08 13:08:28-06","2021-05-05 14:30:26-05" 431,4389,"Machine Learning (ML)",1,"The purpose of the Machine Learning (ML) Domain Team is to develop code and documentation to illustrate ML best practices in the N3C Data Enclave and to collaborate on selected ML topics, such as ML standard operating procedures, graph-based ML, generalizability/racial biases in ML.
Team meetings are held on Mondays at 9:00am PT/12:00pm ET. Please email n3c-ml@googlegroups.com to be added to the calendar invite.
","The purpose of the Machine Learning (ML) Domain Team is to develop code and documentation to illustrate ML best practices in the N3C Data Enclave and to collaborate on selected ML topics.
","n3c-ml@googlegroups.com","https://groups.google.com/forum/#!forum/n3c-ml","Join the Team!","https://drive.google.com/drive/u/2/folders/1yc3mJsg_xdqZxhTg4egNAzAu9vrOpWOl","ML Drive","https://cd2h.slack.com/archives/C01FE9ESPKK","Join the Conversation","2020-11-18 16:27:39-06","2021-05-05 14:53:12-05" 500,4350,"Musculoskeletal (MSK)",0,"The Musculoskeletal Clinical Domain Team aims to characterize musculoskeletal (MSK) symptoms in acute and long-COVID-19, identify predictors of new MSK symptoms or aggravation of pre-existing MSK conditions, develop relevant phenotypes, and establish core domains and core outcome measurement sets.
Team meeting TBD.
","The Musculoskeletal Clinical Domain Team aims to characterize musculoskeletal (MSK) symptoms in acute and long-COVID-19.
","n3c-dt-musculoskeletal@googlegroups.com","https://groups.google.com/u/2/g/n3c-dt-musculoskeletal","Join the Team!","https://drive.google.com/drive/u/2/folders/1Ek_sln7yIyWxW8ARmWf7-RmIpTVOuB79","MSK Drive","https://cd2h.slack.com/archives/C01PLPPREVD","Join the Conversation","2021-03-03 11:28:06-06","2021-05-05 13:51:08-05" 445,4376,"Neurology",0,"The mission of the Neurology Clinical Domain Team is to explore associations between COVID-19 and neurological disease, including associated neurologic symptoms and disease-related neurologic outcomes. Ultimately, we hope to identify relevant biomarkers and possible treatments to prevent neurological injury as a sequela of SARS-CoV-2 infection, both stroke and non-stroke related.
Team meetings are held every other Monday at 1:00pm ET. Please email n3c-dt-neurology@googlegroups.com to be added to the calendar invite.
Neurology Domain Team meetings will focus on topics that can benefit the research community at large by teaching N3C analytics skills while garnering community input on study and analytics design in this domain.
","The Neurology Clinical Domain Team will explore associations between COVID-19 and neurological disease, including associated neurologic symptoms and disease-related neurologic outcomes.
","n3c-dt-neurology@googlegroups.com","https://groups.google.com/g/n3c-dt-neurology","Join the Team!","https://drive.google.com/drive/folders/14KUuR6oD5O6PbTJumxLMSqu2gN27RjD_","Neurology Drive","https://cd2h.slack.com/archives/C01JWDBTALS","Join the Conversation","2020-12-08 13:28:23-06","2021-05-05 14:34:09-05" 539,4541,"Nursing",0,"The Nursing Domain Team aims to apply the holistic perspective of nursing science and related fields to N3C activities through generation of project ideas, analysis of N3C data, identification of data gaps, and generation of resources.
Recurring meeting: Every other Tuesday starting June 22, 2021 10:00am PT/1:00pm ET. Contact n3c-dt-nursing@googlegroups.com for meeting invites.
","The Nursing Domain Team aims to apply the holistic perspective of nursing science and related fields to N3C activities through generation of project ideas, analysis of N3C data, identification of data gaps, and generation of resources.
","n3c-dt-nursing@googlegroups.com ","https://groups.google.com/g/n3c-dt-nursing","Join the Team!","https://drive.google.com/drive/u/0/folders/1qhalFTTOp85J0Q27BLlxGd45lOxl_ffs","Nursing Drive","https://cd2h.slack.com/archives/C01UB6M73D5","Join the Conversation","2021-04-19 13:43:28-05","2021-06-09 18:14:50-05" 440,5034,"OMOP to OBO",1,"
Electronic health record (EHR) data alone are insufficient to address many important questions about the causes of disease. EHR data characterize populations, care, and outcomes, but are divorced from our accumulated knowledge of the biological mechanisms that produce those outcomes. Linking the observations in EHRs with related biomedical knowledge will greatly expand the scope of EHR-based research. This requires that both EHR data and biomedical knowledge be rendered and linked to one another in a standardized and computable form. Significant progress in this linking has been achieved in the OMOP2OBO mapping effort led by Tiffany Callahan. These mappings relate OMOP standard concepts for representing EHR data to OBO ontologies for representing biomedical knowledge.
The goal of this working group is to demonstrate the use of these mappings in support of important new investigations of COVID-19. As the mappings provide a means for introducing domain knowledge expertise, they also have the potential to benefit observational analyses by reducing the inclusion of noisy variables.
Phenopackets
Meeting time: Team meetings are held bi-weekly on Fridays at 10:00am PT / 1:00pm ET starting 01/07/22.
Meeting invitation: OMOP to OBO meeting
","Linking the observations in EHRs with related biomedical knowledge will greatly expand the scope of EHR-based research. The goal of this working group is to demonstrate the use of these mappings in support of important new investigations of COVID-19.
","n3c-dt-omop-obo@googlegroups.com","https://groups.google.com/u/2/g/n3c-dt-omop-obo","Join the Team!","https://drive.google.com/drive/folders/1jlz24aBke4K_p_xYF7_miAaqByExwMZ1","OMOP to OBO Drive","https://cd2h.slack.com/archives/C01RBK4N5UH","Join the Conversation","2020-11-25 17:03:30-06","2022-01-18 17:38:56-06" 367,4499,"Oncology",0,"The Oncology Clinical Domain Team is studying outcomes of cancer patients who contract COVID-19. Cancer phenotypes and concept sets using OMOP data definitions in the N3C Data Enclave are continuously being developed and refined. We are utilizing this data to (1) characterize a cohort of COVID-19 patients with cancer within N3C; (2) identify cancer subpopulations and predictors of increased risk of death or severe complications due to COVID-19; (3) study the prevalence of symptoms and complications caused by the COVID-19 sequelae, including post-acute sequelae; (4) examine the impact of COVID-19 on cancer care, and (5) investigate the effects of cancer therapies and interventions on outcomes of patients infected with COVID-19. Our team includes a diverse range of clinical, epidemiological informatics data and logic liaisons, and statistical expertise.
Team meeting every Tuesday 8:00am PT/11:00am ET. Please email n3c-tt-oncology@googlegroups.com for meeting invite.
","
The Oncology Clinical Domain Team is studying outcomes of cancer patients who contract COVID-19.
","n3c-tt-oncology@googlegroups.com","https://groups.google.com/forum/#!forum/n3c-tt-oncology","Join the Team!","https://drive.google.com/drive/u/0/folders/1LVsdcP0nOy9132AoSGVOJ-pSfn2OxQ1o","Oncology Drive","https://cd2h.slack.com/archives/C018CU4SWM7","Join the Conversation","2020-10-02 15:00:35-05","2021-05-20 12:44:54-05" 521,4947,"Pain, Substance Use Disorder, and Behavioral Health",0,"The Pain, Substance Use Disorder, and Behavioral Health team aims to answer questions regarding the impact of COVID-19 on pain, substance use, and mood. These conditions are impacted by isolation, and the amplification of Long COVID symptoms may have a significant impact on their functional status. The team works on the COVID-19's impact on stigma and health disparities for patients with pain, substance use disorder, and co-morbid mental health diagnoses.
Team meeting TBD.
","The Pain, Substance Use Disorder, and Behavioral Health team aims to answer questions regarding the impact of COVID-19 on pain, substance use, and mood.
","n3c-dt-pain@googlegroups.com","https://groups.google.com/u/2/g/n3c-dt-pain","Join the Team!","https://drive.google.com/drive/u/2/folders/1cilqIJ-yNlpYVgzEkCW-6j1mDw1mtiA5","Pain, Substance Use Disorder & Behavioral Health","https://cd2h.slack.com/archives/C01T02HLHNZ","Join the Conversation","2021-03-29 11:42:30-05","2021-11-15 11:41:03-06" 373,4851,"Pediatrics",0,"Meeting Time: 4th Monday of each month at 3pm EST
The Pediatrics Clinical Domain Team aims to study the unique impact of COVID-19 on children from birth to young adulthood.
Please email n3c-tt-peds@googlegroups.com for meeting invite.
","The Pediatrics Clinical Domain Team aims to study the unique impact of COVID-19 on children from birth to young adulthood.
","n3c-tt-peds@googlegroups.com","https://groups.google.com/forum/#!forum/n3c-tt-peds","Join the Team!","https://drive.google.com/drive/u/0/folders/1jwPU_dvY49EWYVBGHzTkg8f-qd9IyGvo","Pediatrics Drive","https://cd2h.slack.com/archives/C01CSJB3732","Join the Conversation","2020-10-05 12:32:51-05","2021-09-28 15:17:33-05" 476,5031,"Perioperative",0,"The Perioperative Domain Team is focused on understanding the impact of COVID-19 on the treatment and outcomes of surgical patients. The domain team?s goal is to better understand the role COVID-19 plays in relation to the management of surgical patients. The Perioperative Domain Team seeks to develop evidence that is directly relevant to the perioperative surgical complications post-COVID diagnosis. This information may provide surgical teams a better understanding of the associated risks and implement plans that improve surgical outcomes.
Meeting time: Team meetings take place on the 2nd and 4th Friday of the month at 10:00am PT/1:00pm ET.
","The Perioperative Domain Team is focused on understanding the impact of COVID-19 on the treatment and outcomes of surgical patients.
","n3c-dt-perioperative@googlegroups.com","https://groups.google.com/u/2/g/n3c-dt-perioperative","Join the Team!","https://drive.google.com/drive/folders/15deT1DEgko4hF8jrvOcTKX7eyIL8_u_j","Perioperative Drive","https://cd2h.slack.com/archives/C01LSNZP0UX","Join the Conversation","2021-02-05 16:01:14-06","2022-01-18 10:33:09-06" 344,4362,"Pharma - Commercial",1,"The vision of the Pharma-Commercial Domain Team is to maximize engagement with commercial groups to support the increased use and utility of N3C resources and community for research on COVID-19. Because the effort is not related to a specific scientific objective, the focus is mainly on enablement vs. specific scientific research questions.
Team meeting every Monday at 3:00pm ET. Please register here.
","The vision of the Pharma-Commercial Domain Team is to maximize engagement with commercial groups to support the increased use and utility of N3C resources and community for research on COVID-19.
","n3c-tt-pharma-commercial@googlegroups.com","https://groups.google.com/g/n3c-tt-pharma-commercial","Join the Team!","https://drive.google.com/drive/u/0/folders/1HqwFRrDiNkrZjklem9NaMKfGtU6mTQXA","Pharma - Commercial Drive","https://cd2h.slack.com/archives/C01C8EZEYD7","Join the Conversation","2020-10-01 01:11:04-05","2021-05-05 14:09:48-05" 368,4380,"Pharmacoepidemiology",0,"The Pharmacoepidemiology Clinical Domain Team aims to help design the best scenarios for drugs already in use and to provide support for the best possible trials. The overall goal is to evaluate important, empirically testable hypotheses regarding the use, safety, and effectiveness of therapies for treating COVID-19 using a limited dataset from the N3C Data Enclave. These data will provide urgently needed information for deploying therapeutic agents to treat patients with COVID-19 infection.
Team meetings are held every other Monday at 4:00pm ET. Please email n3c-tt-pharmacoepidemiology@googlegroups.com to be added to the calendar invite.
","The goal of the Pharmacoepidemiology Clinical Domain Team is to evaluate important, empirically testable hypotheses regarding the use, safety, and effectiveness of therapies for COVID-19 using a limited dataset from the N3C.
","n3c-tt-pharmacoepidemiology@googlegroups.com","https://groups.google.com/g/n3c-tt-pharmacoepidemiology/","Join the Team!","https://drive.google.com/drive/u/0/folders/1a-cQ3DjxYIzdj4CsuVUYRRCKe6mIDCs0","Pharmacoepidemiology Drive","https://cd2h.slack.com/archives/C01904V30BD","Join the Conversation","2020-10-02 15:02:44-05","2021-05-05 14:39:49-05" 342,4353,"Pregnancy",0,"The Pregnancy Clinical Domain Team aims to leverage N3C data to gain insights into pressing COVID-19 questions around pregnancy. The goal is to understand incidence, timing, and severity in pregnant women, maternal and infant outcomes, and the associated characteristics (clinical, demographic, environmental.)
Team meetings are held on Mondays at 1:00pm PT/4:00pm ET.
","The Pregnancy Clinical Domain Team aims to leverage N3C data to gain insights into pressing COVID-19 questions around pregnancy.
","n3c-tt-pregnancy@googlegroups.com","https://groups.google.com/forum/#!forum/n3c-tt-pregnancy","Join the Team!","https://drive.google.com/drive/u/0/folders/1JG3o6R9vMtoHJVOWiTRxo64jVh5aQVsH","Pregnancy Drive","https://cd2h.slack.com/archives/C018JSKQUQ1","Join the Conversation","2020-10-01 01:01:41-05","2021-05-05 13:55:18-05" 449,5251,"Rural Health ",0,"The Rural Health Domain Team seeks to understand the epidemiology, utilization, treatment, and outcomes of the COVID-19 pandemic in rural communities. The overarching goal is to develop better evidence for potential differences in the COVID-19 epidemic response and outcomes for rural health care centers and rural dwellers. Studying the at-risk populations and unique challenges faced by rural communities during and after the pandemic may provide opportunities for improving rural health and health care.
Meeting time: Team meetings are held at 4:00 pm EST on the first Monday of the month starting 01/03/22. Please email n3c-dt-rural-health@googlegroups.com to be added to the calendar invite.
","The Rural Health Domain Team seeks to understand the epidemiology, utilization, treatment, and outcomes of the COVID-19 pandemic in rural communities. The overarching goal is to develop better evidence for potential differences in the COVID-19 epidemic response and outcomes for rural health care centers and rural dwellers.
","n3c-dt-rural-health@googlegroups.com","https://groups.google.com/g/n3c-dt-rural-health","Join the Team!","https://drive.google.com/drive/u/0/folders/1RXALZPUek95MIOrl9L2bhapalqVwCt0S","Rural Health Drive","https://cd2h.slack.com/archives/C01GT7NM23Y","Join the Conversation","2020-12-16 14:31:14-06","2022-04-28 10:21:21-05" 529,4857,"Sleep",0,"The goal of the Sleep Domain Team is to support the design and execution of studies that are leveraging sleep disorders and related phenotypes. We are focusing on understanding the contribution of sleep disorders and their threat on short and long term consequences of COVID-19. We are also planning to establish data ingestion approaches for novel sleep-related data elements, including results from sleep study reports, PAP adherence data, physiological time series, and wearables.
Team meetings to be held Tuesdays at 7:00am PT/10:00am ET. Please email n3c-dt-sleep@googlegroups.com to be added to the calendar invite.
","The goal of the Sleep Domain Team is to support the design and execution of studies that are leveraging sleep disorders and related phenotypes.
","n3c-dt-sleep@googlegroups.com ","https://groups.google.com/g/n3c-dt-sleep","Join the Team!","https://drive.google.com/drive/u/0/folders/16cSDXB6Draq4Q4YMiLNLNrBFaDHm6JFp|https://drive.google.com/drive/u/0/folders/16cSDXB6Draq4Q4YMiLNLNrBFaDHm6JFp","Sleep Drive","https://cd2h.slack.com/archives/C01SWCKTX7H|https://cd2h.slack.com/archives/C01SWCKTX7H","Join the Conversation","2021-04-05 14:07:42-05","2021-10-06 09:51:31-05" 343,4385,"Social Determinants of Health (SDoH)",0,"The goal of the Social Determinants of Health (SDoH) Clinical Domain Team is to identify at least three questions that either validate current research or answer new questions for the following categories: local policy around COVID-19, impact of groups experiencing resource challenges, and impact of the pandemic on inequalities.
Team meetings are held every other Wednesday at 12:00pm PT/3:00pm ET. Please email n3c-tt-sdoh@googlegroups.com to be added to the calendar invite.
","The goal of the Social Determinants of Health (SDoH) Clinical Domain Team is to identify at least three questions that either validate current research or answer new questions for the following categories: local policy around COVID-19, impact of groups experiencing resource challenges, and impact of the pandemic on inequalities.
","n3c-tt-sdoh@googlegroups.com","https://groups.google.com/forum/#!forum/n3c-tt-sdoh","Join the Team!","https://drive.google.com/drive/u/0/folders/1LVsdcP0nOy9132AoSGVOJ-pSfn2OxQ1o","SDoH Drive","https://cd2h.slack.com/archives/C016FRM8Q4T","Join the Conversation","2020-10-01 01:01:42-05","2021-05-05 14:44:20-05"